Celprogen announces a scaled-down 3D printed human pancreas with PLA and stem cells
Stem cell research company, Celprogen, says they have successfully finished printing a 3D Pancreas. The organ has been made with flexible PLA (polylactic acide) to build the structure and then feeded with adult human pancreatic stem cells.
These 3D printed pancreas, made at a 1/5 scale of that of an adult human body, are made by 3D printing the scaffold in a biocompatible material like flexible PLA, which is coated with ECM and the populated with three T225 human Pancreatic Stem Cells 36097-24-T225, and with human adult pancreatic cells 3002-04-T225. This flexible PLA scaffold allows the seeded pancreatic stem cells to potentially differentiate into an adult functional pancreas.
The company says "the present invention relates to 3D organ printing programs at Celprogen that identify potential future use in transplants of major organ systems". Celprogen is currently working on validating a 3D printed human heart from flexible PLA, and also the pancreas. The 3D printed heart is being presented at the American Society of Cell Biology Annual meeting to be held in San Francisco, California. The 3D printed heart is utilized as a model for screening potential drug candidates for cardiac toxicity.
Celprogen is a global Stem Cell Research & Therapeutics company founded in 2002, which is developing a proprietary portfolio of unique therapeutics products and life science research tools that includes genetic engineering technologies, stem cell technologies for regenerative medicine, as well as bio-engineering products for tissue & organ transplants.